In Dark Heresy, players take on roles as Acolytes of an Inquisitor, standing at the front line of a great and secret war to root out threats that imperil all of humanity. Should they fail, entire worlds, systems, and sectors will fall to endless night.

Dark Heresy Second Edition is a roleplaying game of danger, mystery, and brutal violence set in the decaying far future of Warhammer 40,000. Players assume the roles of defenders of humanity and embark on hazardous adventures in the darkest frontiers of the 41st Millennium. On the orders of an Inquisitor, at the front lines of a great and secret war, they root out dangers that imperil all of humanity. In Dark Heresy Second Edition, players explore the new Ashkelon Sector and bring to life epic tales where it is always a minute from eternal midnight and only their combined efforts can defeat those foes that threaten humanity and stave off the end for one more day. They can never rest, for the multitudes of terrors desiring humanity's extinction are ever-present.